U-GEMMs

Cytokines

SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice. 

Mice
Strain Name:C57BL/6Smoc-Gdf15em(hGDF15)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215002
Mice
Strain Name:C57BL/6Smoc-Hgfem1(hHGF)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200235
Mice
Strain Name:C57BL/6Smoc-Il10tm4(hIL10)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000063
Research Application:Cytokine humanization model;drug screening
Mice
Strain Name:C57BL/6Smoc-Il11em1(hIL11)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-204981
Mice
Strain Name:C57BL/6Smoc-Il11em1(hIL11)Il11ra1tm1(hIL11RA)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210372
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Il12atm3(hIL12A)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000056
Research Application:Cytokine humanization model;drug screening
Mice
Strain Name:C57BL/6Smoc-Il12atm3(hIL12A)Il12betm3(hIL12B)Il12rb1tm1(hIL12RB1)Il12rb2tm1(hIL12RB2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220057
Mice
Strain Name:C57BL/6Smoc-Il12betm3(hIL12B)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000057
Research Application:Cytokine humanization model;drug screening
Mice
Strain Name:C57BL/6Smoc-Il13em2(hIL13)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190069
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:BALB/cAnSmoc-Il13em2(hIL13)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220019
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