U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210357
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C.B6-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-234662
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Tnfsf9em1(hTNFSF9)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234521
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9em1(hTNFRSF9) Cd27em1(hCD27) Smoc
Strain State:Developing | Cat. NO.:NM-XA-234928
Mice
Strain Name:C57BL/6Smoc-Tnfsf9em1(hTNFSF9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00048
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Abcc2tm1(hABCC2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200254
Mice
Strain Name:C57BL/6Smoc-Ace2em3(hACE2-flag-Wpre-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200218
Research Application:Corona virus related research
Mice
Strain Name:C57BL/6Smoc-Tg(CAG-hACE2-IRES-Luciferase-WPRE-polyA-CAG-hAXL-WPRE-polyA)Smoc
Strain State:Developing | Cat. NO.:NM-TG-220132
Mice
Strain Name:C57BL/6Smoc-Acod1tm1(hACOD1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234692
Mice
Strain Name:C57BL/6Smoc-Adam17tm(hADAM17)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220260
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