U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Apoc3em1(hAPOC3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225050
Mice
Strain Name:C57BL/6Smoc-Apoetm4(hAPOE2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190013
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Apoetm3(hAPOE3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190003
Research Application:Cardiovascular disease
Mice
Strain Name:C57BL/6Smoc-Apoetm2(hAPOE4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190002
Research Application:Cardiovascular disease
Mice
Strain Name:C57BL/6Smoc-Apoeem1hAPOE4-R158CSmoc
Strain State:Developing | Cat. NO.:NM-KI-232326
Mice
Strain Name:C57BL/6Smoc-Apptm(hAPP)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220224
Mice
Strain Name:C57BL/6Smoc-Apptm3(hAppNL-F)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000087
Research Application:Alzheimer's disease research
Mice
Strain Name:C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000088
Research Application:Alzheimer's disease research
Mice
Strain Name:C57BL/6Smoc-Tnfsf13em(hTNFSF13)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220521
Mice
Strain Name:C57BL/6Smoc-Aqp4em1(hAQP4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210001
Research Application:drug screening
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