SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Cd276tm2(hCD276)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210349
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Vtcn1em1(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190004
Research Application：Immune-related
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Strain Name：C57BL/6Smoc-Vtcn1em2(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190075
Research Application：Immunotherapy,Cancer research,Drug screening
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Strain Name：C57BL/6Smoc-Btlaem2(hBTLA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190040
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Btlaem1(hBTLA)/Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000044
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Ccr8em3(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220074
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Strain Name：C57BL/6Smoc-Tigittm3(hTIGIT)Ccr8em3(hCCR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220073
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Strain Name：C57BL/6Smoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210435
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Strain Name：C57BL/6Smoc-Ccr8em1(hCCR8)Pdcd1em1(hPDCD1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210400
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Strain Name：C57BL/6Smoc-Bsgtm1(hBSG)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000021
Research Application：Immunotherapy,drug screening
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