U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Cd274em2(hPD-L1)Cd28em2(hCD28)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210370
Research Application:inmmue therapy;drug screening
Mice
Strain Name:BALB/cAnSmoc-Cd274em(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220028
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd27tm3(hCD27)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200274
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd28em2(hCD28)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210019
Research Application:tumor research;inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Nt5eem2(NT5E)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210356
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Sema4dem1(hSemA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190034
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hCD274)Kdrtm2(hKDR)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000102
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1lg2em1(hPDCD1LG2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190050
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:BALB/cAnSmoc-Pdcd1lg2em1(hPDCD1LG2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190061
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Plk1tm1(hPLK1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225083
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