U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Folh1em1(hPSMA-Wpre-PA)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200240
Mice
Strain Name:C57BL/6Smoc-Ptpn1tm1(hPTPN1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225059
Mice
Strain Name:C57BL/6Smoc-Pvrtm1(hPVR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190012
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000084
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Sdc1em1(hSDC1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000026
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Sema4dem1(hSEMA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00117
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Serpina1etm1(hSERPINA1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225055
Mice
Strain Name:C57BL/6Smoc-Sort1em1(hSORT1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225035
Mice
Strain Name:C57BL/6Smoc-Tfrctm1(hTFRC)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215059
Mice
Strain Name:C57BL/6Smoc-Trp53tm1(hTP53)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225052
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