hIL12B
Nomenclature
C57BL/6Smoc-Il12betm3(hIL12B)/Smoc
Cat. NO.
NM-HU-2000057
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Il12b
Model Description
Validation Data
Fig1. Detection of IL12B expression in thymus by RT-PCR.
Wild type: only one band at 260 bp with primers F1/R1(mIl12b);
Heterozygous: one band at 260 bp with primers F1/R1(mIl12b) and one band at 260 bp with primers F2/R2(hIL12B);
Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig 2. Detection of hIL12B expression in plasma by ELISA.
Abbr. HO, homozygous; HE, heterozygous; WT, wild type.
Note. hIL12B and C57BL/6 mice were i.p. injected with LPS(10mg/kg) for 2h.
Fig 3. Detection of mIL12B expression in plasma by ELISA.
Abbr. HO, homozygous; HE, heterozygous; WT, wild type.
Note. hIL12B and C57BL/6 mice were i.p. injected with LPS(10mg/kg) for 2h.
Fig4. Detection of human IL12P70 and mouse IL12P70 expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Note. hIL12A/hIL12B and C57BL/6 mice were i.p. injected with LPS for 2h.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more
