hC1S
Nomenclature
C57BL/6Smoc-C1s1em1(hC1S)/Smoc
Cat. NO.
NM-HU-2000077
Strain State
Repository Live
Gene Summary
Gene Symbol
C1s1
Model Description
Validation Data
Fig1. Detection of C1S1 expression in bladder by RT-PCR. Wild type: only one band at 396 bp with primers F1/R1(mC1s1); Homozygous: only one band at 294 bp with primers F2/R2(hC1S1); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Detection of hC1S1 expression in serum by ELISA (n=8). Abbr. HO, homozygous; WT, wild type.
Fig3. Detection of mC3 and mC5 expression in serum hC1S1 mice by ELISA (n=3). Abbr. HO, homozygous; WT, wild type.
Fig .4 Detection of classical complement pathway activity in hC1S mice by ELISA.
Abbr. HO, homozygous; WT, wild type; PC, Postive Control; NC, Negative Control. Unpaired t test were used, n.s. p>0.05.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more