U-GEMMs

Cytokines

SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice. 

Mice
Strain Name:C57BL/6Smoc-Igs2em(pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220128
Mice
Strain Name:C57BL/6Smoc-Ccl1em2(hCCL1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000074
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Ccl4em1(hCCL4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210013
Research Application:drug screening
Mice
Strain Name:C57BL/6Smoc-CCL5tm1(hCCL5)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210014
Research Application:drug screening
Mice
Strain Name:C57BL/6Smoc-Csf1tm2(CSF1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190043
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Csf1tm2(CSF1)Csf1rem3(hCSF1R)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200273
Mice
Strain Name:BALB/cAnSmoc-Csf1tm2(CSF1)Csf1rem3(hCSF1R)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220016
Mice
Strain Name:C57BL/6Smoc-Csf2tm1(CSF2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190046
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cxcl13tm1(hCXCL13)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225079
Mice
Strain Name:C57BL/6Smoc-Cxcl16em(hCXCL16)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215000
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