U-GEMMs

Metabolic Targets

SMOC has developed a set of mouse models expressing humanized metabolic targets. These models are suitable to assess the efficacy of drugs targeting metabolic pathways proteins in fully immunocompetent mice.

Mice
Strain Name:C57BL/6Smoc-Igs2em1(pAlb-hHAO1 CDS-hHAO1 3'UTR-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-231910
Mice
Strain Name:C57BL/6Smoc-Adora2btm(hADORA2B)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220424
Mice
Strain Name:C57BL/6Smoc-Tg(hAGT)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-230035
Mice
Strain Name:C57BL/6Smoc-Albem3(ALB)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200003
Research Application:Drug screening
Mice
Strain Name:C57BL/6Smoc-Angptl3em2(hANGPTL3)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-210037
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Angptl3em1(hANGPTL3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210036
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Angptl4tm(hANGPTL4)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220285
Mice
Strain Name:C57BL/6Smoc-Apobtm2(hAPOB)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-231781
Mice
Strain Name:C57BL/6Smoc-Apoc3em1(hAPOC3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225050
Mice
Strain Name:C57BL/6Smoc-Apoetm4(hAPOE2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190013
Research Application:Immune-related
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