U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Apoc3tm1(pAlb-hREN-WPRE-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-235088
Mice
Strain Name:C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-200002
Research Application:corona virus related research
Mice
Strain Name:C57BL/6Smoc-Igs2em(pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220128
Mice
Strain Name:FVB-Igs2em1(rIns1-Cre-WPRE-pA-Insulator-Insulator-CAG-loxP-STOP-loxP-hGAST-WPRE-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-240016
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190077
Research Application:Immunotherapy,Cancer research,Drug screening
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Cd3eem2(hCD3E)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210409
Research Application:Drug Screening; Immunotherapy Evaluation
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Tnfrsf4em1(hTNFRSF4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200272
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(h4-1BB)Pdcd1em1(hPDCD1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200279
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210357
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C.B6-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234662
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