U-GEMMs

Cytokines

SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice. 

Mice
Strain Name:NOD-PrkdcscidIl2rgem1Il3em4(hIL3)/Smoc
Strain State:Repository Live | Cat. NO.:NM-NSG-007
Research Application:Immunotherapy,drug screening
Mice
Strain Name:NOD-PrkdcscidIl2rgem1Tg(hIL3-hCSF2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-215006
Mice
Strain Name:C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190065
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:BALB/cAnSmoc-Il3tm(hIL3)Csf2tm(hCSF2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-230358
Mice
Strain Name:C57BL/6Smoc-Il3tm1(hIL3)Csf2tm1(CSF2)Csf1tm2(CSF1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200271
Mice
Strain Name:C57BL/6Smoc-Il31em2(IL31)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200008
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Il33tm2(hIL33)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000069
Research Application:Cytokine humanization model;drug screening
Mice
Strain Name:NMG-Tg(hIL34)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-220431
Mice
Strain Name:C57BL/6Smoc-Il4tm3(hIL4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190071
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:NOD-PrkdcscidIl2rgem1Tg(hIL4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-215004
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