SMOC has developed a set of mouse models expressing humanized cytokines receptors. These models are suitable to assess the efficacy of drugs targeting cytokines receptors in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210414
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Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220144
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Strain Name：C57BL/6Smoc-Il2rbtm1(hIL2RB)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000055
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200007
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210354
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Tslptm2(hTSLP)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-232383
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Strain Name：C57BL/6Smoc-Il4ratm1(hIL4R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190008
Research Application：Immune-related
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Strain Name：C57BL/6Smoc-Il6raem1(hIL6R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00044
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State：Developing | Cat. NO.：NM-HU-210027
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Tgtn(hLILRA4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225074
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