hIL21R

Nomenclature

C57BL/6Smoc-Il21rtm1(hIL21R)Smoc

Cat. NO.

NM-HU-210031

Strain State

Repository Live

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Gene Summary

Gene Symbol
IL21R

Synonyms

NILR

NCBI ID

60504

MGI ID

1890475

Ensembl ID

ENSMUSG00000030745

Pubmed

IL21R

Human Ortholog

IL21R

Model Description

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.
Research Application：inmmue therapy；drug screening

Validation Data

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Fig 1. Detection of IL21R expression on spleen-derived activated T cells and B cells in hIL21/hIL21R dKI mice.

Note. Splenocytes from C57BL/6 and homozygous hIL21R mice were stimulated with anti-mCD3 antibody in vitro.


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