hCXCR6

Nomenclature

C57BL/6Smoc-Cxcr6em(hCXCR6)Smoc

Cat. NO.

NM-HU-215001

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Cxcr6

Model Description

The endogenous mice Cxcr6 gene was replaced by human CXCR6 gene.

Validation Data

image.png

Fig1. Detection of CXCR6 expression in spleen  by RT-PCR. Wild type: only one band at 423 bp with primers F1/R1(mCxcr6);Homozygous: only one band at 206 bp with primers F2/R2(hCXCR6); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hCXCR6 expression on NKT cells in spleen in hCXCR6 KI mice.

image.png


Fig3. Detection of hCXCR6 expression on splenocyte-derived activated T cells in hCXCR6 KI mice. 

Note. Splenocytes from C57BL/6 and homozygous hCXCR6 mice were stimulated with anti-mCD3 and anti-mCD28 in vitro. 





You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more