Cat. NO.


Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol

Model Description

The endogenous mouse Ccr5 gene was replaced by human CCR5 gene.
Research Application:Immunotherapy,drug screening

Validation Data

NM-HU-2000065 hCCR5.png

Fig1. Analysis of CCR5 gene expression in the spleen by RT-PCR.

Mouse Ccr5 mRNA was detectable by P1/2(869bp), human CCR5 mRNA was detectable by P1/3(607bp), 

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human CCR5 and mouse Ccr5 in the spleen.

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