The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
Mice
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Strain Name:C57BL/6Smoc-Tgtn(pAlb-hLPA-3’UTR-pA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-231782
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Mice
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Strain Name:C57BL/6Smoc-Tg(pAlb-hLPA-WPRE-pA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-232196
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Mice
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Strain Name:C57BL/6Smoc-Tg(pAtp4b-hCLDN18.2)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-220197
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Mice
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Strain Name:C57BL/6Smoc-Tg(pCdh16-hENPP3)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-220195
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Mice
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Strain Name:NOD-PrkdcscidIl2rg-Tg(pCMV-hIL34-pA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-220433
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Mice
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Strain Name:C57BL/6Smoc-Tgtn(pPbsn-hMICB-pA)1Smoc
Strain State:Developing | Cat. NO.:NM-TG-234894
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Mice
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Strain Name:C57BL/6Smoc-Tgtn(pWap-ERBB2)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-225013
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00081
Research Application:cancer research;Immunotherapy,drug screening
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190093
Research Application:Chemical Genetics studies.The inhibitory GiDREADD(hM4Di) could silence the activity of neurons following administration of CNO.
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GqDREADD(hM3Dq)-P2A-mCitrine-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190106
Research Application:Chemical Genetics studies.The GqDREADD(hM3Dq) could stimulate the activity of neurons following administration of CNO.
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