hTLR9
Nomenclature
C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Cat. NO.
NM-HU-18016
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Tlr9
Model Description
This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.
Validation Data
Fig.1 Detection of hTLR9 and mTlr9 expression in Peripheral blood in WT C57BL/6 and HO hTLR9 KI mice.
Fig.2 Detection of hTLR9 and mTlr9 expression in Spleen in WT C57BL/6 and HO hTLR9 KI mice.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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