hTLR7
Nomenclature
C57BL/6Smoc-Tlr7tm1(hTLR7)Smoc
Cat. NO.
NM-HU-18027
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
TLR7
Model Description
The endogenous mouse Tlr7 gene was replaced by humanTLR7 gene.
Research Application：Immunotherapy,Cancer research,Drug screening
*Literature published using this strain should indicate: hTLR7 mice (Cat. NO. NM-HU-18027) were purchased from Shanghai Model Organisms Center, Inc..
Validation Data
Fig.1 Detection of hTLR7 and mTlr7 expression on Myeloid cells in WT C57BL/6 and HO hTLR7 KI mice .
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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