R26-LSL-hEZH2-IRES-Luc-2A-tdTomato
Nomenclature
C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc
Cat. NO.
NM-KI-18053
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Gt(ROSA)26Sor
Model Description
A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.
Research Application：Tumor research; drug screening
*Literature published using this strain should indicate: R26-LSL-hEZH2-IRES-Luc-2A-tdTomato mice (Cat. NO. NM-KI-18053) were purchased from Shanghai Model Organisms Center, Inc..
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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