hTLR4

Nomenclature

C57BL/6Smoc-Tlr4em2(hTLR4)/Smoc

Cat. NO.

NM-HU-2000025

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Tlr4

Synonyms

Lps; Ly87; Ran/M1; Rasl2-8

NCBI ID

21898

MGI ID

96824

Ensembl ID

ENSMUSG00000039005

Pubmed

Tlr4

Human Ortholog

TLR4

Model Description

The endogenous mouse Tlr4 gene was replaced by human TLR4 gene.
Research Application：Immunotherapy,drug screening

Validation Data

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Fig1. Detection of TLR4 expression in bladder by RT-PCR. Wild type: only one band at 227 bp with primers F1/R1(mTlr4);Homozygous: only one band at 399 bp with primers F2/R2(hTLR4); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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