hVEGFA

Nomenclature

C57BL/6Smoc-Vegfatm1(hVEGFA)/Smoc

Cat. NO.

NM-HU-2000028

Strain State

Repository Live

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Gene Summary

Gene Symbol
Vegfa

Synonyms

Vpf; Vegf

NCBI ID

22339

MGI ID

103178

Ensembl ID

ENSMUSG00000023951

Pubmed

Vegfa

Human Ortholog

VEGFA

Model Description

The endogenous mouse Vegfa gene was replaced by human VEGFA gene. While hVEGFA(2)(Stock No.NM-HU-204984) mice function similarly to hVEGFA mice,for more detailed information please contact our technical advisor.
Research Application：Immunotherapy,drug screening

Validation Data

image.png

Fig1. Detection of VEGFA expression in lung by RT-PCR. 

Wild type: only one band at 251 bp with primers F1/R1(mVegfa); Homozygous: only one band at 282 bp with primers F2/R2(hVEGFA);  

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig 2. Detection of hVEGFA expression in lung homogenate by ELISA. 

Note. The human VEGFA ELISA kit cross-reacted with mVEGFA and humanized VEGFA.

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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