huHSC-(NMG)

Nomenclature

huHSC-(NMG)

Cat. NO.

NM-NSG-017

Strain State

Repository Live

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Model Description

After irradiation, NMG mice are injected with CD34+ hematopoietic stem cells (CD34+ HSC).

Research Application：Infectious disease; Gene therapy; Cancer; Drug targets without cross-reactivity; Immunogenicity study

Publications

Breaking Spatiotemporal Barriers of Immunogenic Chemotherapy via an Endoplasmic Reticulum Membrane-Assisted Liposomal Drug Delivery
References：ACS Nano

The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation
References：Cellular & Molecular Immunology

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