hRSPO1

Nomenclature

C57BL/6Smoc-Rspo1tm1(hRSPO1)Smoc

Cat. NO.

NM-HU-225041

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Rspo1

Synonyms

Rspondin; R-spondin

NCBI ID

192199

MGI ID

2183426

Ensembl ID

ENSMUSG00000028871

Pubmed

Rspo1

Human Ortholog

RSPO1

Model Description

The endogenous mouse Rspo1 gene was replaced by human RSPO1 gene.

Validation Data

image.png

Fig1. Detection of RSPO1 expression in lung by RT-PCR. 

Wild type: only one band at 183 bp with primers F1/R1 (mRspo1);

Homozygous: only one band at 210 bp with primers F2/R2 (hRSPO1);


Abbr. M, DNA marker; HO, homozygous;  WT, wild type.

image.png

Fig2. Detection of human and mouse RSPO1 expression in liver homogenate by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

Note. The human and mouse RSPO1 ELISA kit cross-reacted with mouse RSPO1 and humanized RSPO1.

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