NMG-Hc
Nomenclature
NOD-PrkdcscidIl2rgem1Hcem3(c.645InsTA)Smoc
Cat. NO.
NM-NSG-012
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Hc
Model Description
These NMG mice carry a c.645InsTA mutation of Hc gene.
Research Application：Its potential use to compare complement-dependent and complement-independent cytotoxic activity mediated by therapeutic mAbs.
*Literature published using this strain should indicate: NMG-Hc mice (Cat. NO. NM-NSG-012) were purchased from Shanghai Model Organisms Center, Inc..
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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