Upk3a-KO

Nomenclature

C57BL/6Smoc-Upk3aem1Smoc

Cat. NO.

NM-KO-201095

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Upk3a

Synonyms

UP3a， Upk3， UPIII， 1110017C07Rik

NCBI ID

22270

MGI ID

98914

Ensembl ID

ENSMUSG00000022435

Pubmed

Upk3a

Human Ortholog

UPK3A

Model Description

Exon 2-3 of Upk3a gene was deleted to generate Upk3a knockout mice.

Disease Connection

Vesicoureteral Reflux

Phenotype(s)

MGI:2654027

Reference(s)

Hu P, Deng FM, Liang FX, Hu CM, Auerbach AB, Shapiro E, Wu XR, Kachar B, Sun TT, Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux. J Cell Biol. 2000 Nov 27;151(5):961-72

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more