U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Trem2em4(hTRem2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000083
Research Application:Alzheimer's disease research;drug screening
Mice
Strain Name:C57BL/6Smoc-Trem2tm(hTRem2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220502
Mice
Strain Name:C57BL/6Smoc-Trim11tm1(hTRIM11)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234697
Mice
Strain Name:C57BL/6Smoc-Tacstd2em(hTACSTD2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215022
Mice
Strain Name:C57BL/6Smoc-Tacstd2em(hTACSTD2)Cd274em1(hPD-L1)Cd28em2(hCD28)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-234816
Mice
Strain Name:C57BL/6Smoc-Trpa1tm1(hTRPA1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234698
Mice
Strain Name:C57BL/6Smoc-Tshrtm1(hTSHR)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232156
Mice
Strain Name:C57BL/6Smoc-Tshrtm2(hTSHR)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-232157
Mice
Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000064
Research Application:Asthma research;drug screening
Mice
Strain Name:NOD-PrkdcscidIl2rgem1Tslptm(hTSLP)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220426
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