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Gene Summary

Gene Symbol

Model Description

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Research Application:immunodeficiency,immune system,transplantation research

Validation Data


Fig1. Detection of B2m expression in cerebellum by RT-PCR. 

Wild type: only one band at 139 bp with primers F1/R1(mB2m);

Abbr. M, DNA marker; HO, homozygous;  WT, wild type.


Fig2. Expression characterization of mouse MHC I and MHC II in bone marrow, blood, spleen in B2m-KO(M-NSG) mice.

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