SmocMab Fully-human Antibody Transgenic Mouse

Key features of SmocMab platform:

  • Rapid Antibody Discovery: Tailored antibodies specific to your antigen in just 3 months. 

  • Dual-Technology: Combines fully humanized mice with knockout (KO) or point mutation (PM) homozygous models. 

  • Proven Success: Greatly shortens the fully antibody generation timeline. 

  • Broad Applications: Ideal for oncology, auto-immune diseases, and more.


You can order SmocMab mice for your research, we also provide CRO service based on SmocMab Mice, such as pharmaceutical research and development services, research and development of antibodies, early evaluation in the field of implementation of new drugs, development of pharmaceutical preparations and pharmaceuticals, biological research and analysis, pharmaceutical evaluation, etc.


 Schematic of Humanization in The SmocMab Mouse

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Fig1. Mouse variable regions of the heavy and k light chains are replaced by the human counterparts in situ.


SmocMab Mouse demonstrates a similar immune system to that of WT mouse

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Fig2. Analysis of leukocytes cell subpopulation in Spleen.


SmocMab Mouse demonstrates highly similar immune responses compared to WT mouseimage.png

Fig3. Robust immune response in C57BL/6 and SmocMab elicited by three panels of antigens.

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